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According to the labeling of dabigatran in
2019-06-05

According to the labeling of dabigatran in Japan, patients to be considered for the prescription of the lower dose of 220mg/day are as follows: (1) aged ≥70 years, (2) with moderate renal impairment (ClCr 30–50mL/min), (3) concomitant use of a p-glycoprotein inhibitor, and (4) history of hemorrhage
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br Interpretation of identified genetic variants and genetic
2019-06-05

Interpretation of identified genetic variants and genetic counseling Although the current expert consensus statement recommends that comprehensive or BrS1 (SCN5A) targeted BrS genetic testing can be useful for genetic testing [63], not all the published SCN5A mutations in BrS have been subjected
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orexin a Worldwide there are an estimated specialist surgeon
2019-06-05

Worldwide, there are an estimated 1 112 727 specialist surgeons (IQR 1 059 158–1 177 912), 550 134 anaesthesiologists (529 008–572 916) and 483 357 obstetricians (456 093–517 638; ). Low-income and lower-middle-income countries, representing 48% of the global population, have 20% of this workforce,
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Varios republicanos espa oles de s lida posici n econ
2019-06-05

Varios republicanos españoles de sólida posición económica residentes en México habrían recibido esta carta de extorsión, entre ellos personajes como: Fernando Rodríguez Miaja, Máximo Muñoz, Jerónimo Bugeda o Juan Simeón Vidarte, quien se apresuró ampk inhibitors denunciarlo a las autoridades. Sean
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Resulta importante resaltar el surgimiento de nuevos patrone
2019-06-05

Resulta importante resaltar el surgimiento de nuevos patrones de lectura e interpretación de los escenarios políticos en Latinoamérica, porque ello explica su desplazamiento en los modos de leer que hasta 1960 habían caracterizado sus ensayos. Estos descubrimientos propiciados por la Revolución pusi
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Even so the purpose of our Comment
2019-06-05

Even so, the purpose of our Comment was to counter the notion that is useful to think in terms of “Ebola suspects” and their ostensible options, while reminding us to question whether the fetishisation of isolation over treatment was “an institutionalized form of non-assistance” that resulted in “a
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br Hybrid approach It is
2019-06-05

Hybrid approach It is still not certain whether a single or a staged approach is safer and more effective. Natale et al. [31] performed a combined closed-chest epicardial monopolar radiofrequency ablation through a transabdominal transdiaphragmatic single port and catheter-based transseptal endoc
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In the context of cataract surgery Nathan Congdon and collea
2019-06-05

In the context of cataract surgery, Nathan Congdon and colleagues (August, p e37) propose the possibility of using early postoperative assessment of all patients or late assessment only of those who return for follow-up without additional prompting as practicable methods to improve long-term patient
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c-met inhibitor In addition we are continuing our
2019-06-01

In addition, we are continuing our regular editorial policies of commissioning more specialised Clinical Reviews and Series across Group to provide a more focused and in-depth assessment for key diseases. And beyond providing knowledge and information, we want to encourage academic and practising c
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A second methodological issue concerns the accuracy of the e
2019-06-01

A second methodological issue concerns the accuracy of the exposure measurement. Without accurate measurement, different methods for calculating attributable risk that are equivalent in theory are not guaranteed to give compatible results in practice. Previous experience with carcinogenic infections
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IL can induce phagocytosis cytoskeleton rearrangement gene
2019-06-01

IL-15 can induce phagocytosis, cytoskeleton rearrangement, gene expression, de novo protein synthesis and can delay apoptosis in human neutrophils [15]. Production of chemokines, cytokines and natural inhibitors is increased in IL-15 induced neutrophils, including CXCL8 (IL-8) [16], IL-1beta, IL-1RI
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The main inherited arrhythmogenic causes of SCD
2019-06-01

The main inherited arrhythmogenic causes of SCD in the young are summarized in Fig. 1. These arrhythmogenic disorders include familial long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tachycardia (CPVT), Brugada syndrome (BrS), idiopathic ventricular fibrillation, early repolarizat
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Despu s de marcharse de
2019-06-01

Después de marcharse de la India Paz publica , una obra ensayística que sirve como continuación de y comentario sobre la revuelta de los estudiantes mexicanos que precedió gingerol la masacre. En este libro Paz postula que la corrupción del lenguaje es la primera señal de un problema grave a nivel
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br Materials and methods Eculizumab levels were measured at
2019-06-01

Materials and methods Eculizumab levels were measured at Cambridge Biomedical using a manual ELISA method in which the microtitre plates are coated with C5, then blocked. Standards, controls, and unknowns were added. After incubation and washing, mouse anti-human IgG4 horseradish peroxidase (HRP)
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The study by Mijiti and colleagues also illustrates that
2019-06-01

The study by Mijiti and colleagues also illustrates that, besides medical factors, social determinants of health—poverty, education, geography, customs, etc—also play an important role in tuberculosis control. Owing to the low socioeconomic status and poor social health environment, tuberculosis mai
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