• Prednisone prephase was initiated and led to immediate

  2019-05-21

  

  Prednisone prephase was initiated and led to immediate improvement of clinical status. However, tumour size did not decrease within the prolonged prephase of 11 days (Fig. 1b). Despite additional cyclophosphamide (2×200mg/m2), the patient showed deteriorating clinical condition and fever reappeared

• In conclusion through a series of

  2019-05-21

  

  In conclusion, through a series of experiments we showed that our antigen LALF32-51-E7 combined with alum adjuvant promotes a Th1 immune response and consequently an anti-tumor response in the TC-1 tumor model. Based on our results, we suggest not to underestimate the capacity of Al(OH)3 as adjuvant

• Long QT syndrome LQTS a rare inheritable arrhythmia first de

  2019-05-21

  

  Long QT syndrome (LQTS), a rare inheritable arrhythmia first described by Romano and Ward et al. in the 1960s, is characterized by the prolongation of the QT interval on surface ECGs and an increased risk of potentially fatal ventricular arrhythmias, especially torsade de pointes . In 1995, after ye

• Given the recognized effects of bisphosphonates in

  2019-05-21

  

  Given the recognized effects of bisphosphonates in metastatic breast cancer [14,15] and that potential anticancer effects have been demonstrated in preclinical [16], translational [17], patients with cancer therapy-induced bone loss [18] and Phos-tag based-studies [19,20] a number of clinical trial

• TAK-242 Well designed operational research is needed

  2019-05-21

  

  Well designed operational research is needed to refine this starting point. Research is also needed to find out whether prophylactic valganciclovir treatment in high-risk patients might reduce AIDS mortality as well as blindness, as substantial data suggest. WHO leadership is needed to provide cytom

• In the case reported by

  2019-05-20

  

  In the case reported by Goldstein et al. [2], a Riata ST lead (St. Jude Medical, Sylmar, CA, USA) was used. The authors did not mention whether the lead was a dual-coil system or not. If the lead was a single-coil system, the possibility of an HV short circuit between the RV coil conductor and the d

• br Case report The patient then

  2019-05-20

  

  Case report The patient then achieved disease-free status as noted in a series of routine image studies during regular follow-up at our oncology clinic. In November 2011, she presented due to hematuria for several days. Diagnostic cystoscopy showed a mass lesion on the urinary bladder. Whole body

• Numerous animal studies have demonstrated beyond doubt

  2019-05-20

  

  Numerous animal studies have demonstrated beyond doubt that effective inhibition of osteoclastogenesis or osteoclast function significantly reduces metastatic tumour growth in bone [13–20]. Likewise, clinical trials in patients with non-metastatic or metastatic cancers established that treatment wit

• glucosamine sulfate br There is growing recognition that chi

  2019-05-20

  

  There is growing recognition that children bear a substantial burden of tuberculosis morbidity and mortality. However, in regions where the diagnosis is contingent on smear microscopy, the burden attributable to children, who usually have paucibacillary disease, is grossly underestimated. The down

• br The west African outbreak of Ebola virus

  2019-05-20

  

  The 2014–15 west African outbreak of Ebola virus disease is unprecedented in scale, especially in Sierra Leone, which as of May 15, 2015, had reported 8598 confirmed cases and 3538 confirmed Ebola-related deaths. Sierra Leone\'s response to this emergency has been compromised by a fragile health s

• In Blake Alkire and colleagues now provide additional measur

  2019-05-20

  

  In , Blake Alkire and colleagues now provide additional measures to help us gain political priority on the public health agendas. In this study, Alkire and colleagues modelled access to surgery in 180 countries on the basis of four criteria: timeliness, surgical capacity, safety, and affordability.

• br El hispanismo criollo de vasconcelos

  2019-05-20

  

  El hispanismo criollo de vasconcelos Conclusiones: “próspero” vasconcelos Sin la disciplina personal ni el pragmatismo, inculcado por la pequeña escuela texana, Vasconcelos no hubiera logrado todo lo que se propuso desde joven. El peligro de la dispersión y la pereza latinoamericana ya lo habí

• De esta manera los estados latinoamericanos

  2019-05-20

  

  De esta manera, los estados latinoamericanos se han redefinido desde aquello que puede denominarse cautela y desconfianza. Dichos estados son la materialización de la desconfianza histórica, de la amplitud del margen del conocimiento, de la apreciación de que no todo va bien y por supuesto, de una “

• dextromethorphan hydrobromide Desde mediados de la d cada de

  2019-05-20

  

  Desde mediados de la década de los sesenta, la embajada argentina pedía informes sobre las actividades políticas en general y sobre las consideradas subversivas en Guatemala. A juicio de la embajada, en 1978 no se podía analizar la “ola de violencia” en Guatemala sin incluirla en el contexto de lo q

• Clofarabine associated capillary leak syndrome

  2019-05-20

  

  Clofarabine-associated capillary leak syndrome, attributed to cytokine release, is characterized by hypotension, tachycardia, and tachypnea, and can be fatal. Alternatively, Type I hypersensitivity to clofarabine can occur in up to 5% of patients, and is also a contraindication to further therapy pe

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